Cosentyx (Secukinumab) for the Treatment of Adult Onset Pityriasis Rubra Pilaris



Status:Recruiting
Healthy:No
Age Range:18 - Any
Updated:12/14/2018
Start Date:April 1, 2018
End Date:April 15, 2020

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Cosentyx (Secukinumab) for the Treatment of Adult Onset Pityriasis Rubra Pilaris: A Single Arm, Open-label Exploratory Trial

The primary objective of this study is to assess the potential effectiveness of Cosentyx in
the treatment of adult-onset Pityriasis Rubra Pilaris or PRP.


Inclusion Criteria

Informed subject consent will be obtained from those patients meeting the following
inclusion criteria:

- Male and female patients 18 years or older.

- Clinical and/or histopathological diagnosis of PRP

- Candidate for systemic therapy (PASI ≥ 10)

- Body surface area of involvement ≥ 10%

- Good general health as confirmed by medical history

- Patients who are willing and capable of cooperating to the extent and degree required
by the protocol; and

- Patients who read and sign an approved informed consent for this study

Exclusion Criteria

Patients are to be excluded based on the following criteria:

- Vulnerable study population

- Pregnant or nursing women

- Women planning a pregnancy within the study period

- Human immunodeficiency virus (HIV) positivity

- Known history of adverse reaction to Cosentyx

- Known history of hepatitis B, hepatitis C, or tuberculosis

- Personal or family history of inflammatory bowel disease
We found this trial at
2
sites
4500 San Pablo Rd S
Jacksonville, Florida 32224
(904) 953-2000
Principal Investigator: Jason C Sluzevich
Phone: 904-953-7214
Mayo Clinic Florida Thousands of people come to Mayo Clinic in Jacksonville, Fla., annually for...
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13400 E. Shea Blvd.
Scottsdale, Arizona 85259
480-301-8000
Principal Investigator: Aaron R Mangold, MD
Phone: 480-301-4714
Mayo Clinic Arizona Mayo Clinic in Arizona provides medical care for thousands of people from...
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Scottsdale, AZ
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