An Investigational Immuno-therapy Study for Safety of Nivolumab in Combination With Ipilimumab to Treat Advanced Cancers



Status:Recruiting
Conditions:Lung Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:12/16/2018
Start Date:September 14, 2016
End Date:November 17, 2021
Contact:Recruiting sites have contact information. Please contact the sites directly. If there is no contact information, please email:
Email:Clinical.Trials@bms.com

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

A Phase 3b/4 Safety Trial of Flat Dose Nivolumab In Combination With Ipilimumab in Participants With Non-Small Cell Lung Cancer

A study to evaluate the safety of Nivolumab given in combination with Ipilimumab in patients
with advanced cancers. The initial group will enroll patients with newly diagnosed Stage 4 or
non-small cell lung cancer that has come back.


For more information regarding Bristol-Myers Squibb Clinical Trial participation, please
visit www.BMSStudyConnect.com

Inclusion Criteria:

- Histologically confirmed Stage 4 or recurrent non-small cell lung cancer

- Eastern Cooperative Oncology Group (ECOG) score 0-1 (Physically able to carry out
light housework or office work through to being fully active as you were before
cancer)

- No prior systemic anticancer therapy (including EGFR and ALK inhibitors)

- Tissue or Programmed death-ligand 1 (PD-L1) results available

Cohort 1A Inclusion Criteria:

- Eastern Cooperative Oncology Group (ECOG) score 2 or

- Eastern Cooperative Oncology Group (ECOG) score 0-1 and one disease specific criteria
as listed in the protocol

Cohort C Inclusion Criteria:

- High Tumor Mutation Burden

Exclusion Criteria:

- Untreated brain metastases

- An active malignancy that requires concurrent intervention

- Active, known or suspected autoimmune disease

- Carcinomatous meningitis, which means there is inflammation of the covering of the
brain, caused by cancer

Other protocol defined inclusion/exclusion criteria could apply
We found this trial at
71
sites
Local Institution
Berkeley, California 94704
?
mi
from
Berkeley, CA
Click here to add this to my saved trials
Memorial Cancer Institute
3700 Johnson Street
Hollywood, Florida 33021
Phone: 310-206-0179
?
mi
from
Hollywood, FL
Click here to add this to my saved trials
University of Arkansas for Medical Sciences
529 West Markham Street
Little Rock, Arkansas 72205
(501) 686-7000
Phone: 501-686-8274
University of Arkansas for Medical Sciences The University of Arkansas for Medical Sciences (UAMS) in...
?
mi
from
Little Rock, AR
Click here to add this to my saved trials
Central Coast Medical Oncology Corporation
220 S Palisade Dr # 204
Santa Maria, California 93454
Phone: 310-206-0179
?
mi
from
Santa Maria, CA
Click here to add this to my saved trials
Lehigh Valley Health Network
Allentown, Pennsylvania 18105
Phone: 610-402-1642
?
mi
from
Allentown, PA
Click here to add this to my saved trials
University Cancer and Blood Center LLC
Athens, Georgia 30607
Phone: 706-353-2990
?
mi
from
Athens, GA
Click here to add this to my saved trials
Winship Cancer Institute
Atlanta, Georgia 30322
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Northside Hospital
1000 Johnson Ferry Rd NE
Atlanta, Georgia 30342
(404) 851-8000
Phone: 770-496-9457
Northside Hospital Northside Hospital-Atlanta (in Sandy Springs) opened in 1970. The original facility had 250...
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Texas Oncology, PA at South Austin Cancer Center
Austin, Texas 78745
Phone: 512-447-2202
?
mi
from
Austin, TX
Click here to add this to my saved trials
CBCC Global Research
6501 Truxtun Avenue
Bakersfield, California 93309
Phone: 310-206-0179
?
mi
from
Bakersfield, CA
Click here to add this to my saved trials
Essex Oncology of North Jersey
Belleville, New Jersey 07109
Phone: 973-751-8880
?
mi
from
Belleville, NJ
Click here to add this to my saved trials
Alabama Oncology
Birmingham, Alabama 35223
Phone: 205-263-9746
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Local Institution
Boise, Idaho 83712
?
mi
from
Boise, ID
Click here to add this to my saved trials
Local Institution
Bronx, New York 10467
?
mi
from
Bronx, NY
Click here to add this to my saved trials
Instituto Medico Especializado Alexander Fleming
Capital Federal, Buenos Aires
?
mi
from
Capital Federal,
Click here to add this to my saved trials
Local Institution
Chandler, Arizona 85224
?
mi
from
Chandler, AZ
Click here to add this to my saved trials
Charleston Hematology/Oncology Associates, Pa
Charleston, South Carolina 29403
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Tennessee Oncology PLLC
Chattanooga, Tennessee 37404
Phone: 877-691-7274
?
mi
from
Chattanooga, TN
Click here to add this to my saved trials
Oncology Hematology Care
5053 Wooster Rd
Cincinnati, Ohio 45226
(513) 751-2273
Phone: 513-751-2273
Oncology Hematology Care Our more than 60 physicians and advanced practice providers throughout neighborhood offices...
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
MetroHealth Med Ctr
2500 Metrohealth Dr
Cleveland, Ohio 44109
(216) 778-7800
Phone: 216-778-4568
MetroHealth Med Ctr The MetroHealth System is one of the largest, most comprehensive health care...
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
Maryland Oncology Hematology PA
Columbia, Maryland 21044
Phone: 410-964-2212
?
mi
from
Columbia, MD
Click here to add this to my saved trials
Local Institution
Corvallis, Oregon 97330
?
mi
from
Corvallis, OR
Click here to add this to my saved trials
Texas Oncology, PA
Dallas, Texas 75246
Phone: 214-265-2080
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Rocky Mountain Cancer Center
Denver, Colorado 80218
Phone: 303-388-4876
?
mi
from
Denver, CO
Click here to add this to my saved trials
DUMC
Durham, North Carolina 27710
?
mi
from
Durham, NC
Click here to add this to my saved trials
Minnesota Oncology Hematology, PA
Edina, Minnesota 55435
Phone: 612-884-6300
?
mi
from
Edina, MN
Click here to add this to my saved trials
Providence Regional Cancer Partnership
1717 13th St
Everett, Washington 98201
(425) 297-5500
Providence Regional Cancer Partnership Founded in 2007, the Providence Regional Cancer Partnership is the result...
?
mi
from
Everett, WA
Click here to add this to my saved trials
Virginia Cancer Specialists, PC
8503 Arlington Blvd., Ste. 400
Fairfax, Virginia 22031
(703) 280-5390
Phone: 703-208-5390
Virginia Cancer Specialists, PC Now the world's most advanced cancer treatment capabilities can be found...
?
mi
from
Fairfax, VA
Click here to add this to my saved trials
Texas Oncology-Fort Worth 12th Ave.
Fort Worth, Texas 76104
Phone: 817-850-2011
?
mi
from
Fort Worth, TX
Click here to add this to my saved trials
St. Francis Cancer Treatment Center
Grand Island, Nebraska 68803
Phone: 308-398-6518
?
mi
from
Grand Island, NE
Click here to add this to my saved trials
St. Mary's Hospital Regional Cancer Center
Grand Junction, Colorado 81501
Phone: 310-206-0179
?
mi
from
Grand Junction, CO
Click here to add this to my saved trials
Marin Cancer Care, Inc.
Greenbrae, California 94904
?
mi
from
Greenbrae, CA
Click here to add this to my saved trials
Local Institution
Hot Springs, Arkansas 71913
?
mi
from
Hot Springs, AR
Click here to add this to my saved trials
Local Institution
Indianapolis, Indiana 46260
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Jackson Oncology Associates
Jackson, Mississippi 39202
Phone: 601-974-5547
?
mi
from
Jackson, MS
Click here to add this to my saved trials
Cancer Specialists Of North Fl
Jacksonville, Florida 32256
Phone: 904-363-7462
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
Local Institution
La Jolla, California 92093
?
mi
from
La Jolla, CA
Click here to add this to my saved trials
Local Institution
Langhorne, Pennsylvania 19047
?
mi
from
Langhorne, PA
Click here to add this to my saved trials
Comprehensive Cancer Centers of Nevada
9280 W. Sunset Road Suite 100
Las Vegas, Nevada 89148
702.952.1251
Phone: 702-952-3400
Comprehensive Cancer Centers of Nevada Comprehensive Cancer Centers of Nevada (CCCN) is the award-winning multidisciplinary...
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Kentucky One Health St. Joseph East Cancer Center
150 North Eagle Creek Drive
Lexington, Kentucky 40509
Phone: 720-874-1346
?
mi
from
Lexington, KY
Click here to add this to my saved trials
Saint Barnabas Medical Cancer Center
94 Old Short Hills Road
Livingston, New Jersey 07039
Phone: 973-322-5325
?
mi
from
Livingston, NJ
Click here to add this to my saved trials
Texas Oncology - Longview
Longview, Texas 75601
Phone: 903-579-9800
?
mi
from
Longview, TX
Click here to add this to my saved trials
Los Angeles Hematology/Oncology Medical Group
Los Angeles, California 90017
Phone: 213-977-1214
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
UCLA
Los Angeles, California 90095
(310) 825-4321
Phone: 310-206-8309
UCLA UCLA's primary purpose as a public research university is the creation, dissemination, preservation and...
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Local Institution
Macon, Georgia 31201
?
mi
from
Macon, GA
Click here to add this to my saved trials
Local Institution
Morristown, New Jersey
?
mi
from
Morristown, NJ
Click here to add this to my saved trials
Tennessee Oncology, PLLC
250 25th Ave N, Ste 100
Nashville, Tennessee 37023
615-320-5090
Phone: 877-691-7274
Tennessee Oncology, PLLC Since 1976 Tennessee Oncology has been providing quality cancer care. In 2013,...
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Illinois Cancer Specialists
Niles, Illinois 60714
Phone: 847-827-9060
?
mi
from
Niles, IL
Click here to add this to my saved trials
Florida Cancer Affiliates - Ocala
433 Southwest 10th Street
Ocala, Florida 34471
Phone: 352-732-4938
?
mi
from
Ocala, FL
Click here to add this to my saved trials
Local Institution
Oklahoma City, Oklahoma 73103
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
Arizona Oncology Assoc, Pc-Hal
Phoenix, Arizona 85016
Phone: 928-204-4198
?
mi
from
Phoenix, AZ
Click here to add this to my saved trials
Allegheny Health Network
PIttsburgh, Pennsylvania 15212
Phone: 412-235-1316
?
mi
from
PIttsburgh, PA
Click here to add this to my saved trials
Local Institution
Pittsburgh, Pennsylvania 15240
?
mi
from
Pittsburgh, PA
Click here to add this to my saved trials
Texas Oncology-Plano East
Plano, Texas 75075
Phone: 972-867-3577
?
mi
from
Plano, TX
Click here to add this to my saved trials
Local Institution
Portland, Oregon 97201
?
mi
from
Portland, OR
Click here to add this to my saved trials
Torrance Health Association
Redondo Beach, California 90277
Phone: 310-750-3376
?
mi
from
Redondo Beach, CA
Click here to add this to my saved trials
Cancer Care Specialists
Reno, Nevada 89511
?
mi
from
Reno, NV
Click here to add this to my saved trials
Valley Medical Center
Renton, Washington 98055
?
mi
from
Renton, WA
Click here to add this to my saved trials
Virginia Cancer Institute
Richmond, Virginia 23235
Phone: 804-288-7159
?
mi
from
Richmond, VA
Click here to add this to my saved trials
Local Institution
San Diego, California 92123
?
mi
from
San Diego, CA
Click here to add this to my saved trials
Coastal Integrative Cancer Care
San Luis Obispo, California 93401
Phone: 310-206-0179
?
mi
from
San Luis Obispo, CA
Click here to add this to my saved trials
Guthrie Medical Group, PC
Sayre, Pennsylvania 18840
Phone: 570-887-2141
?
mi
from
Sayre, PA
Click here to add this to my saved trials
Local Institution
Skokie, Illinois 60077
?
mi
from
Skokie, IL
Click here to add this to my saved trials
Medical Oncology Associates
Spokane, Washington 99208
?
mi
from
Spokane, WA
Click here to add this to my saved trials
Willamette Valley Cancer Center
Springfield, Oregon 97477
Phone: 541-988-0656
?
mi
from
Springfield, OR
Click here to add this to my saved trials
Gene Upshaw Memorial Tahoe Forest Cancer Center
Truckee, California 96161
Phone: 530-582-6438
?
mi
from
Truckee, CA
Click here to add this to my saved trials
Arizona Oncol Assoc Dba (Hem Onc Physicians&Extenders) Hope
Tucson, Arizona 85704
Phone: 520-797-4468
?
mi
from
Tucson, AZ
Click here to add this to my saved trials
Texas Oncology Cancer Care And Research Center
Waco, Texas 76712
Phone: 254-399-0741
?
mi
from
Waco, TX
Click here to add this to my saved trials
Innovative Clinical Research Institute, LLC
Whittier, California 90603
Phone: 562-693-4477
?
mi
from
Whittier, CA
Click here to add this to my saved trials
Cancer Center of Kansas
818 N. Emporia, #403
Wichita, Kansas 67214
(316) 262-4467
Phone: 316-262-4467
Cancer Center of Kansas The physicians of Cancer Center are hematologists and oncologists. The staff...
?
mi
from
Wichita, KS
Click here to add this to my saved trials
Wake Forest Baptist Health
Winston-Salem, North Carolina 27157
?
mi
from
Winston-Salem, NC
Click here to add this to my saved trials