Study of Nivolumab in Unresectable Advanced or Recurrent Esophageal Cancer



Status:Recruiting
Conditions:Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:20 - Any
Updated:5/24/2017
Start Date:December 2015
Contact:Ono Pharmaceutical Co. Ltd Corporate Communications
Email:y.tani@ono.co.jp

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ONO-4538 Phase III Study A Multicenter, Randomized, Open-label Study in Patients With Unresectable Advanced or Recurrent Esophageal Cancer

The purpose of study is to evaluate the efficacy and safety of Nivolumab in unresectable
advanced or recurrent esophageal cancer patients who have failed in standard chemotherapies.


Inclusion Criteria:

- Men & women ≥20 years of age

- Histologically confirmed unresectable advanced or recurrent esophageal cancer

- Refractory to or intolerant of standard therapy

- ECOG Performance Status score 0 or 1

- A life expectancy of at least 3 months

Exclusion Criteria:

- Current or past history of severe hypersensitivity to any other antibody products

- Patients with multiple primary cancers

- Patients with any metastasis in the brain or meninx that is symptomatic or requires
treatment

- Patients with active, known or suspected autoimmune disease
We found this trial at
9
sites
24 Sturtevant St
Orlando, Florida 32806
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185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
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Boston, MA
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2220 Pierce Ave
Nashville, Tennessee 37232
615-936-8422
Vanderbilt-Ingram Cancer Center The Vanderbilt-Ingram Cancer Center, located in Nashville, Tenn., brings together the clinical...
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Nashville, TN
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20 Duke Clinic Cir
Durham, North Carolina 27710
(888) 275-3853
Duke Cancer Institute Leading-edge cancer care and research have been a hallmark of Duke Medicine...
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Durham, NC
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Gilbert, Arizona 85234
Phone: 520-235-8420
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Gilbert, AZ
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1515 Holcombe Blvd
Houston, Texas 77030
 713-792-2121
University of Texas M.D. Anderson Cancer Center The mission of The University of Texas MD...
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Houston, TX
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Odense C,
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Washington, D.C., District of Columbia 20007
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Washington, D.C.,
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Westwood, Kansas 66205
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Westwood, KS
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