Hypoxia at Multiple Wavelengths of Light



Status:Completed
Healthy:No
Age Range:18 - 35
Updated:5/3/2014
Start Date:September 2013
End Date:December 2013
Contact:David MacLeod, MD
Email:david.macleod@duke.edu
Phone:919-681-6437

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Effect of Induced Hypoxia at Multiple Wavelengths

The purpose of the study is to assess the effect of progressive, incremental hypoxia at
multiple wavelengths of light.

No additional information is required.

Inclusion Criteria:

- Is between 18 and 35 years of age

- Is American Society Anesthesiologist status 1

- Has a BMI between 18 and 30

Exclusion Criteria:

- Currently taking any medications other than birth control pills

- Has participate in an investigational drug study within one month prior to the start
of the study

- Fails the Allen's Test to confirm patency of the colateral artery

- Subject is female with a positive pregnancy test, or is female and is unwilling to
use effective birth control between the time of screening and study termination

- Has a positive urine continine or drug test

- Has an reported allergy to Lidocaine

- Has anemia or other hemoglobinopathy

- Has a room air saturation less than 95% by pulse oximetry

- Has an abnormal EKG

- Has an abnormal pulmonary function test via spirometry

- Is intolerant to a breathing mask apparatus

- Has a COHb greater than 3%, or MetHb greater than 2%

- Has another condition, which in the opinion of the principle investigator would not
be suitable for participation in the study

- Is unwilling or unable to provide informed consent or comply with the study
procedures
We found this trial at
1
site
Durham, North Carolina 27710
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Durham, NC
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