Multiple Dose Trial Examining Dose Range, Escalation and Efficacy of Oral Semaglutide in Subjects With Type 2 Diabetes



Status:Completed
Conditions:Diabetes, Diabetes
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - Any
Updated:2/3/2018
Start Date:December 2, 2013
End Date:December 11, 2014

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This trial is conducted globally. The aim of the trial is to examine the dose range,
escalation and efficacy of oral semaglutide in subjects with type 2 diabetes.


Inclusion Criteria:

- BMI above or equal to 25 and below or equal to 40 kg/m^2

- Subjects diagnosed with T2D (Type 2 diabetes) treated with diet and exercise and/or
who have been on a stable dose of metformin for at least 30 days prior to screening

- HbA1c 7.0-9.5% (53-80 mmol/mol) (both inclusive)

Exclusion Criteria:

- Subjects on selected oral medication with a narrow therapeutic window, such as
warfarin, digoxin, tricyclic antidepressants, lithium, aminophylline, theophylline and
anticonvulsants

- History of chronic pancreatitis or idiopathic acute pancreatitis

- Chronic malabsorption, regardless of aetiology

- History of Crohn's disease, ulcerative colitis, or other inflammatory bowel disease

- Treatment with glucose lowering agent(s) other than metformin as stated in the
inclusion criteria in a period of 90 days before the screening visit
We found this trial at
38
sites
Addison, Illinois 60101
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Addison, IL
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Asheville, North Carolina 28801
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Asheville, NC
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Athens, Georgia 30606
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Athens, GA
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Chicago, Illinois 60612
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Chicago, IL
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Chula Vista, California 91910
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Chula Vista, CA
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Colorado Springs, Colorado 80910
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Colorado Springs, CO
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Conyers, Georgia 30094
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Conyers, GA
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Dallas, Texas 75231
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Dallas, TX
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Denver, Colorado 80220
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Denver, CO
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Fargo, North Dakota 58122
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Fargo, ND
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Graz,
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Humboldt, Tennessee 38343
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Humboldt, TN
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Jacksonville, Florida 32207
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Jacksonville, FL
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Jersey Shore, Pennsylvania 17740
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Jersey Shore, PA
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Las Vegas, Nevada 89128
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Las Vegas, NV
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Long Beach, California 90807
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Long Beach, CA
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Miami, Florida 33136
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Miami, FL
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Moncks Corner, South Carolina 29461
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New York, New York 10029
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New York, NY
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Newport News, Virginia 23606
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Newport News, VA
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Norman, Oklahoma 73069
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Norman, OK
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Philadelphia, Pennsylvania 19104
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Philadelphia, PA
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Plantation, Florida 33324
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Plantation, FL
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Poway, California 92064
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Poway, CA
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Raleigh, North Carolina 27610
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Rochester, New York 14609
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Rochester, NY
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Rockville, Maryland 20852
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Salisbury, North Carolina 28144
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San Antonio, Texas 78224
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San Antonio, TX
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Santa Ana, California 92704
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Santa Ana, CA
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South Miami, Florida 33143
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South Miami, FL
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Spring Hill, Tennessee 37174
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Spring Valley, California 91978
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Sugar Land, Texas 77479
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Sugar Land, TX
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Tucson, Arizona 85704
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Tucson, AZ
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Walnut Creek, California 94598
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Walnut Creek, CA
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Wenatchee, Washington 98801
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Wenatchee, WA
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Wichita, Kansas 67205
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Wichita, KS
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