Impact of Fluid Milk on Post-meal Glycemia and Insulinemia in Overwt/Obese Adults



Status:Completed
Conditions:Obesity Weight Loss, Endocrine, Diabetes
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:35 - 65
Updated:4/21/2016
Start Date:August 2013
End Date:September 2015

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Impact of Fluid Milk on Post-meal Glycemia and Insulinemia in Overweight/Obese Adults With Normal or Impaired Glucose Tolerance or Type 2 Diabetes

Blood sugar and insulin levels after a meal may be altered by the food and beverages a
person consumes. Keeping a healthy blood sugar level may help prevent and manage type 2
diabetes and related diseases. This study will look at how drinking different common
beverages (milk, low-fat milk, nonfat milk, orange juice, coffee, and water) with a meal
changes blood sugar and insulin levels.

The broad aim of the proposed research is to evaluate the effects of consuming milk and
non-milk beverages with a breakfast meal on postprandial glucose and insulin responses in
overweight and obese adults with varying levels of glucose tolerance (normal, pre-diabetic,
type 2 diabetes). The investigators expect the consumption of fluid milk with breakfast to
decrease the postprandial glucose response relative to other non-milk beverages (orange
juice and sweetened coffee). Furthermore, the investigators expect that there will be no
difference in the postprandial glucose or insulin response between varieties of fluid milk
(skim, low-fat, and whole).

Inclusion Criteria:

- 35-65 years old,

- BMI between 27-40 kg/m2,

- HbA1C less than 7.5%,

- weight stable (± 4.5 kg) for the previous 3 months

- willing to consume study foods and beverages.

Exclusion Criteria:

- using exogenous insulin,

- currently (or within the past 6 months) following a vigorous exercise regimen, or
weight loss program,

- acute illness,

- smoking,

- pregnant or planning pregnancy in the next 3 months,

- lactose intolerant,

- weight changes of greater than ± 3 kg during the study period
We found this trial at
1
site
West Lafayette, Indiana 47907
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from
West Lafayette, IN
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