Study of Wellness Behaviors as a Function of Oxytocin vs Placebo



Status:Completed
Healthy:No
Age Range:35 - 64
Updated:11/8/2014
Start Date:September 2013
End Date:October 2014
Contact:Ann M Firestine, M.S.
Email:annfire@unc.edu
Phone:919-942-4988

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Affective and Genomic Mediators of Sustained Behavior Change: A Randomized, Dual-blind, Placebo-controlled Experimental Design That Will Examine Wellness Behavior as a Function of Oxytocin vs. Placebo.

The specific aim of this study is to test whether oxytocin (OT) boosts the positive emotion
yield of a new wellness behavior (Lovingkindness meditation or Mindfulness meditation) and
thereby increases nonconscious motives that shape daily behavioral decisions to repeat it,
which in turn foster positive emotions that further augment nonconscious motives in an
upward spiral dynamic.

The proposed research targets three hypotheses: (1) Oxytocin manipulation magnifies (i.e.,
moderates) the positive emotion yield of Lovingkindness meditation; (2) The positive emotion
yield of meditation, which varies by experimental condition, increases the nonconscious
incentive salience of Wellness Behavior-related cues; and (3) Behavioral decisions predict
positive emotions, sparking the relationships among OT manipulation, positive emotion yield,
and nonconscious incentive salience of Wellness Behavior-related cues.


Inclusion Criteria:

- between the ages of 35 and 64 years old.

- Fluent in written and spoken English

- Willingness or interest in learning to meditate

- Computer literate with access to internet (weekly)

Exclusion Criteria:

- Women who are pregnant or breastfeeding

- Individuals on antihypertensive medication

- Individuals who have or have had a regular meditation practice

- Individuals who can read Chinese logographs
We found this trial at
1
site
Chapel Hill, North Carolina 27519
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Chapel Hill, NC
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