Pistachios, Performance, Metabolomics



Status:Completed
Conditions:Other Indications
Therapuetic Areas:Other
Healthy:No
Age Range:18 - 55
Updated:2/7/2015
Start Date:March 2013
End Date:July 2014
Contact:David C Nieman, DrPH
Email:niemandc@appstate.edu
Phone:8287730056

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Influence of Pistachios on Performance and Exercise-induced Inflammation, Oxidative Stress, and Immune Dysfunction in Athletes: a Metabolomics-based Approach.

Ingestion of 3 ounces of pistachio nuts per day for two weeks before and the day of cycling
intensely for 75 kilometers will support substrate utilization during exercise (as
determined through metabolomics) and improve performance compared to water only, and
attenuate inflammation, oxidative stress, and immune dysfunction during 24 hours of
recovery.


Inclusion Criteria:

- Male endurance cyclists

- Capable of exercising for 2.5 h at a high intensity in the lab

- Ages 18-55

- Agree to train normally and stay weight stable.

- Agree to avoid the use of large dose vitamin/mineral supplements

- Agree to avoid herbs and medications that influence inflammation

Exclusion Criteria:

- Regularly take supplements or medicines known to effect inflammation.

- At moderate or high risk for cardiovascular disease.

- Younger than 18 or older than 55 years of age.

- No history of competing in cycling races.
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