Follow-up Protocol for Patients With Cancer/AIDS/Skin Disease

Background:

- Patients enrolled on CCR clinical protocols may require long term follow-up to assess
outcome (e.g., survival) or the effects of prior therapy.

- Keeping the primary treatment protocols open after accrual is complete in order to
follow patients for long term outcome is an administrative burden on investigators and
the IRB.

Objectives:

-To provide follow-up for patients who are long term survivors previously enrolled Center for
Cancer Research (CCR) trial but who may not currently be enrolled on a research protocol.

Eligibility:

-Patients who were previously enrolled on a CCR protocol and who are not eligible for an
active NCI intramural primary research protocol.

Design:

- The medical procedures/tests will be based on the patient's diagnosis, treatment and
supporting clinical information. This is a follow-up study in which only standard tests
and procedures are to be performed.

- Clinical information that is relevant to the patients prior protocols will be collected
for research purposes.

- Procedures that entail more than minimal risk to the patient should not be performed for
research purposes on this protocol.

- ELIGIBILITY CRITERIA:

Patients of any age who were previously enrolled on a CCR protocol.

Not eligible for or unwilling to participate in an active NCI intramural primary research
protocol.

CCR investigator decides it is in the best interests of the patient and the CC for the
patient to be seen in follow-up visits at the NIH.

Patient or Legally Authorized Representative (LAR)/guardian is able to provide informed
consent.