A Study of Rituximab and Bevacizumab in Patients With Follicular Non-Hodgkin's Lymphoma



Status:Archived
Conditions:Lymphoma
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:7/1/2011

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Trial Summary
Trial Overview
Inclusion Criteria

Rituximab +/- Bevacizumab in the Treatment of Patients With Follicular Non-Hodgkin's Lymphoma: A Randomized, Phase II Trial


The purpose of this study is to assess the feasibility, efficacy and safety of adding
bevacizumab to rituximab compared to rituximab alone in patients with previously treated
follicular non-hodgkin's lymphoma (NHL) whose disease has progressed following at least one
previous chemotherapy regimen and not more than 2 previous chemotherapy regimens.


Upon determination of eligibility, patients will randomly be assigned to receive one of two
treatment arms:

- Rituximab

- Rituximab + bevacizumab (Avastin®)

For every 2 patients randomized, 1 will receive treatment number 1 (rituximab), and 1
patient will receive treatment number 2 (rituximab + bevacizumab). This is not a blinded
study, so both the patient and doctor will know which treatment has been assigned.


We found this trial at
17
sites
Graves-Gilbert Clinic
Bowling Green, Kentucky 42101
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Bowling Green, KY
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Florida Cancer Specialists
3840 Broadway
Fort Myers, Florida 33901
(239) 275-6400
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Fort Myers, FL
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Northeast Georgia Heart Center, PC
Gainesville, Florida 30501
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Gainesville, FL
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Integrated Community Oncology Network
9143 Philips Hwy # 560
Jacksonville Beach, Florida 32250
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Jacksonville Beach, FL
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Watson Clinic Center for Research, Inc.
1730
Lakeland, Florida 33805
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Lakeland, FL
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Cancer Institute of Florida, PA - Orlando
2501 N Orange Ave # 235
Orlando, Florida 32804
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from
Orlando, FL
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Hematology Oncology Life Center
Alexandria, Louisiana 71301
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Alexandria, LA
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Baton Rouge General Medical Center
Baton Rouge, Louisiana 70806
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Baton Rouge, LA
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Chattanooga Oncology Hematology Associates
Chattanooga, Tennessee 37404
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from
Chattanooga, TN
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Oncology Hematology Care
5053 Wooster Rd
Cincinnati, Ohio 45226
(513) 751-2273
Oncology Hematology Care Our more than 60 physicians and advanced practice providers throughout neighborhood offices...
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Cincinnati, OH
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Northeast Arkansas Clinic
Jonesboro, Arkansas 72401
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Jonesboro, AR
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Consultants in Blood Disorders and Cancer
Louisville, Kentucky 40207
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Louisville, KY
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WellStar Health System
Marietta, Georgia 30060
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from
Marietta, GA
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Hematology Oncology Associates of Northern NJ
Morristown, New Jersey 07960
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from
Morristown, NJ
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Tennessee Oncology, PLLC
250 25th Ave N, Ste 100
Nashville, Tennessee 37023
615-320-5090
Tennessee Oncology, PLLC Since 1976 Tennessee Oncology has been providing quality cancer care. In 2013,...
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mi
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Nashville, TN
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Nebraska Methodist Hospital
8303 Dodge Street
Omaha, Nebraska 68114
(402) 354–4000
Nebraska Methodist Hospital Methodist Hospital is a general medical and surgical hospital in Omaha, NE....
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from
Omaha, NE
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Spartanburg Regional Health Service District
Spartanburg, South Carolina 29303
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from
Spartanburg, SC
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