Botulinum-assisted Orbital Fat Augmentation With PRP (Platelet-rich-plasma)
Status: | Completed |
---|---|
Healthy: | No |
Age Range: | 21 - 75 |
Updated: | 8/22/2018 |
Start Date: | January 2014 |
End Date: | January 3, 2018 |
immobilization of yoked extra-ocular muscles in the anophthalmic orbit, in conjunction with
platelet-rich-plasma, will improve integration of viable adipocytes injected into orbital fat
platelet-rich-plasma, will improve integration of viable adipocytes injected into orbital fat
Immobilization of tissue (graft, graft bed) is a prerequisite for tissue integration. Since
yoked extra-ocular muscles continue to be stimulated by movements of the seeing eye after fat
injection into the anophthalmic orbit, the use of botulinum toxin(s) can be used to prevent
movement of the orbital tissue bed(s) and improve anchoring of injected fat. Platelet rich
plasma may also improve fat cell anchoring by the action of fibrin on the adhesion process.
This innovation builds on the results of IRB protocols 10.27 and 12.01 as registered with
Clinical Trials.gov
yoked extra-ocular muscles continue to be stimulated by movements of the seeing eye after fat
injection into the anophthalmic orbit, the use of botulinum toxin(s) can be used to prevent
movement of the orbital tissue bed(s) and improve anchoring of injected fat. Platelet rich
plasma may also improve fat cell anchoring by the action of fibrin on the adhesion process.
This innovation builds on the results of IRB protocols 10.27 and 12.01 as registered with
Clinical Trials.gov
Inclusion Criteria:
- anophthalmic enophthalmos in subjects within a 50 mile radius of New York City, grade
0-1 anesthesia risk, ages 21-75
Exclusion Criteria:
- radiated orbits
We found this trial at
1
site
New York, New York
Principal Investigator: Donald M Fox, MD
Phone: 212-772-1500
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