New York State Psychiatric Institute
1051 Riverside Dr
New York, New York 10032
646-774-5000 http://nyspi.org

Use our guide to learn which trials are right for you!

The New York State Psychiatric Institute (NYSPI), established in 1895, was one of the first institutions in the United States to integrate teaching, research and therapeutic approaches to the care of patients with mental illnesses. In 1925, NYSPI affiliated with Presbyterian Hospital, adding general hospital facilities to the Institute's psychiatric services and research laboratories. These treatment, training, and research facilities were supplemented in 1983 by a 14-floor Psychiatric Research Building, the Kolb Annex.

The NYSPI was further modernized in 1998 by opening of a new hospital building to replace the original one. Overlooking the Hudson River and George Washington Bridge, the new Psychiatric Institute provides a state-of-the art environment for patient care, education, and research. The approximately 320,000 square feet offer space for 60 inpatient beds, 23 specialized outpatient research clinics, educational facilities, and research laboratories. Walkway bridges to and from the Kolb Annex and New York Presbyterian Hospital provide comfortable and efficient all-weather avenues for patient and staff travel within the Columbia University Medical Center.

Since its inception, NYSPI has been at the forefront of psychiatry, making major contributions to the clinical care and understanding of the mentally ill. Among these accomplishments are: the discovery of the spirochaetal origin of general paresis, the earliest use of lithium in the United States, the first data describing a genetic predisposition to schizophrenia, leadership in the discovery of the genes causing Huntington's and Wilson's disease, and the development of DSM-III, DSM III-R and DSM-IV.

Through the years, distinguished figures in American psychiatry have served as directors of the Psychiatric Institute, including Drs. Ira Van Gieson, Adolph Meyer, August Hoch, Lawrence Kolb, Edward Sachar and Herbert Pardes. It is now led by a noted academic psychiatrist, Dr. Jeffrey Lieberman. The Institute is the flagship for the Columbia University Department of Psychiatry, for which it is the primary location of research and educational activities.

The Columbia University Department of Psychiatry is located at the Columbia-Presbyterian Medical Center in northern Manhattan, part of an urban neighborhood that is ethnically and economically diverse in a city that has been called the capital of the world. The institutions which comprise the teaching facilities of the Department are described below. Now part of Columbia University, the College of Physicians and Surgeons was founded in 1767 and was the first school in North America to award doctoral degrees in medicine. 'P&S' has developed extensive new facilities over the past few years, including the Hammer Health Sciences Center - a 20-story structure housing an excellent medical library, amphitheatre and teaching facilities. The medical school is considered to be among the finest in America, and has traditionally been one of the nation's primary sources of academicians, investigators and clinical teachers. The core New York Presbyterian Hospital structure, adjacent to the NYSPI, is the 745-bed Milstein Hospital building, which has expanded the hospital's advanced medical procedures and its critical care capability.

We've found
36 trials
at this facility
Cocaine Dependence Clinical Trial
Imaging the Neurobiology of a Behavioral Treatment for Cocaine Dependence
Status: Enrolling
Updated: 9/14/2006
mi
from
New York, NY
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Major Depression Clinical Trial
Interpersonal Therapy for Depression in Breast Cancer
Status: Enrolling, Phase IV
Updated: 12/5/2014
mi
from
New York, NY
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Psychiatry / Psychology Clinical Trial
Tocilizumab as Add-On Treatment For Residual Positive, Negative, and Cognitive Symptoms of Schizophrenia
Status: Enrolling, Phase IV
Updated: 12/3/2015
mi
from
New York, NY
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Immunology / Infectious Diseases, Other Clinical Trial
Return to Work Randomized Controlled Trial: Counseling After Fatigue Treatment in HIV/AIDS
Status: Enrolling
Updated: 11/5/2015
mi
from
New York, NY
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Major Depressive Disorder Clinical Trial
Psychological Mindedness as a Predictor of Success in Cognitive Behavior Therapy for Depression
Status: Enrolling
Updated: 8/27/2015
mi
from
New York, NY
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Opioid Overdose Clinical Trial
Risks and Benefits of Naloxone Prescribing
Status: Enrolling, Phase I
Updated: 8/31/2015
mi
from
New York, NY
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Anorexia Nervosa Clinical Trial
Changing Habits in Anorexia Nervosa: Novel Treatment Development
Status: Enrolling
Updated: 10/19/2015
mi
from
New York, NY
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Posttraumatic Stress Disorder (PTSD) Clinical Trial
Attention-Bias Modification Treatment for PTSD
Status: Enrolling
Updated: 5/4/2015
mi
from
New York, NY
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Attention Deficit Hyperactivity Disorder Clinical Trial
An fMRI Study of Non-Stimulant Treatment of ADHD
Status: Enrolling
Updated: 10/20/2015
mi
from
New York, NY
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Clinical High Risk for Psychosis Clinical Trial
Gabapentin in Patients at Clinical Risk for Psychosis
Status: Enrolling, Phase I, II
Updated: 9/24/2015
mi
from
New York, NY
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Neurology, Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Study Comparing Magnetic Seizure Therapy (MST) to Electroconvulsive Therapy (ECT) for Depression in Older Adults
Status: Enrolling, Phase I, II
Updated: 9/24/2015
mi
from
New York, NY
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Separation Anxiety Disorder Clinical Trial
Vilazodone for Separation Anxiety Disorder
Status: Enrolling, Phase IV
Updated: 10/13/2015
mi
from
New York, NY
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Schizophrenia Clinical Trial
Long Term Study of RBP 7000 in the Treatment of Subjects With Schizophrenia
Status: Enrolling, Phase III
Updated: 7/17/2015
mi
from
New York, NY
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Schizophrenia Clinical Trial
TDCS for Auditory Hallucinations in Schizophrenia
Status: Enrolling
Updated: 3/17/2016
mi
from
New York, NY
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Bipolar Disorder I or II Clinical Trial
Tranylcypromine Treatment of Bipolar Depression
Status: Enrolling, Phase IV
Updated: 12/14/2011
mi
from
New York, NY
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Obsessive Compulsive Disorder Clinical Trial
Attaining and Maintaining Wellness in Obsessive-compulsive Disorder
Status: Enrolling, Phase IV
Updated: 12/3/2015
mi
from
New York, NY
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Neurology, Psychiatry / Psychology Clinical Trial
Olfactory Deficits and Donepezil Treatment in Cognitively Impaired Elderly
Status: Enrolling, Phase IV
Updated: 10/5/2015
mi
from
New York, NY
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Anorexia Nervosa Clinical Trial
Olanzapine Versus Placebo for Outpatients With Anorexia Nervosa
Status: Enrolling
Updated: 5/1/2015
mi
from
New York, NY
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Anorexia Nervosa Clinical Trial
Inpatient Exposure Therapy and Response Prevention & Cognitive Remediation Therapy for Anorexia Nervosa
Status: Enrolling
Updated: 8/2/2010
mi
from
New York, NY
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Cocaine Dependence Clinical Trial
The Effect of Brief Potent Glutamatergic Modulation on Cocaine Dependence
Status: Enrolling, Phase I, II
Updated: 1/30/2015
mi
from
New York, NY
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Cannabis Dependence Clinical Trial
Quetiapine Pharmacotherapy for Cannabis Dependence
Status: Enrolling, Phase II
Updated: 10/2/2012
mi
from
New York, NY
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Attention Deficit Hyperactivity Disorder Clinical Trial
Imaging the Effects of Stimulant Medication on Emotional Lability in Patients With ADHD
Status: Enrolling
Updated: 10/20/2015
mi
from
New York, NY
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Musculoskeletal, Psychiatry / Psychology Clinical Trial
Characterization of the Analgesic Effects of Oral THC and Smoked Marijuana in Non-Treatment Seeking Marijuana Smokers
Status: Enrolling
Updated: 8/26/2008
mi
from
New York, NY
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Neurology, Psychiatry / Psychology Clinical Trial
Treatment of Psychosis and Agitation in Alzheimer's Disease
Status: Enrolling, Phase II
Updated: 12/1/2015
mi
from
New York, NY
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Psychiatry / Psychology Clinical Trial
Medication-Assisted Treatment for Youth With Substance Use Disorders
Status: Enrolling, Phase I
Updated: 10/29/2015
mi
from
New York, NY
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Obsessive-Compulsive Disorder Clinical Trial
Randomized Controlled Trial of Intranasal Ketamine vs. Intranasal Midazolam in Individuals With Obsessive Compulsive Disorder (OCD)
Status: Enrolling, Phase II
Updated: 4/16/2015
mi
from
New York, NY
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Lung Cancer Clinical Trial
Investigation of Cannabis for Pain and Inflammation in Lung Cancer
Status: Upcoming, Phase I
Updated: 2/4/2016
mi
from
New York, NY
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PTSD Clinical Trial
Reflective Function as a Mediator of Interpersonal Psychotherapy (IPT)
Status: Upcoming
Updated: 1/10/2016
mi
from
New York, NY
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Chronic Pain Clinical Trial
Imaging the Effects of rTMS on Chronic Pain
Status: Upcoming, Phase I
Updated: 2/19/2016
mi
from
New York, NY
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Cigarette Smoking Clinical Trial
Effects of Nicotine Replacement Therapy and D-cycloserine on Nicotine Treatment Seekers
Status: Upcoming, Phase II
Updated: 7/22/2013
mi
from
New York, NY
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Post Treatment Lyme Disease Syndrome Clinical Trial
Meditation and Stretching for Post Treatment Lyme Disease Syndrome
Status: Upcoming
Updated: 1/26/2015
mi
from
New York, NY
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Gastroenterology, Psychiatry / Psychology Clinical Trial
Effects of Ibudilast on Oxycodone Self-administration in Opioid Abusers
Status: Enrolling, Phase II
Updated: 2/1/2016
mi
from
New York, NY
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Psychiatry / Psychology Clinical Trial
Kuvan in People With Schizophrenia and Schizoaffective Disorder
Status: Enrolling, Phase I, II
Updated: 3/17/2016
mi
from
New York, NY
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Post-Traumatic Stress Disorder Clinical Trial
Effectiveness of Three Different Psychotherapies for Chronic Post-Traumatic Stress Disorder
Status: Enrolling, Phase III
Updated: 1/25/2016
mi
from
New York, NY
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Obsessive-Compulsive Disorder Clinical Trial
Pilot Study of Ketamine in Adults With Obsessive-Compulsive Disorder (OCD)
Status: Enrolling, Phase II
Updated: 2/29/2016
mi
from
New York, NY
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Healthy Controls Clinical Trial
Biomarker Assessment of Glutamatergic Target Engagement
Status: Enrolling, Phase IV
Updated: 3/17/2016
mi
from
New York, NY
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