New York State Psychiatric Institute
1051 Riverside Dr
New York, New York 10032
646-774-5000 http://nyspi.org

Use our guide to learn which trials are right for you!

The New York State Psychiatric Institute (NYSPI), established in 1895, was one of the first institutions in the United States to integrate teaching, research and therapeutic approaches to the care of patients with mental illnesses. In 1925, NYSPI affiliated with Presbyterian Hospital, adding general hospital facilities to the Institute's psychiatric services and research laboratories. These treatment, training, and research facilities were supplemented in 1983 by a 14-floor Psychiatric Research Building, the Kolb Annex.

The NYSPI was further modernized in 1998 by opening of a new hospital building to replace the original one. Overlooking the Hudson River and George Washington Bridge, the new Psychiatric Institute provides a state-of-the art environment for patient care, education, and research. The approximately 320,000 square feet offer space for 60 inpatient beds, 23 specialized outpatient research clinics, educational facilities, and research laboratories. Walkway bridges to and from the Kolb Annex and New York Presbyterian Hospital provide comfortable and efficient all-weather avenues for patient and staff travel within the Columbia University Medical Center.

Since its inception, NYSPI has been at the forefront of psychiatry, making major contributions to the clinical care and understanding of the mentally ill. Among these accomplishments are: the discovery of the spirochaetal origin of general paresis, the earliest use of lithium in the United States, the first data describing a genetic predisposition to schizophrenia, leadership in the discovery of the genes causing Huntington's and Wilson's disease, and the development of DSM-III, DSM III-R and DSM-IV.

Through the years, distinguished figures in American psychiatry have served as directors of the Psychiatric Institute, including Drs. Ira Van Gieson, Adolph Meyer, August Hoch, Lawrence Kolb, Edward Sachar and Herbert Pardes. It is now led by a noted academic psychiatrist, Dr. Jeffrey Lieberman. The Institute is the flagship for the Columbia University Department of Psychiatry, for which it is the primary location of research and educational activities.

The Columbia University Department of Psychiatry is located at the Columbia-Presbyterian Medical Center in northern Manhattan, part of an urban neighborhood that is ethnically and economically diverse in a city that has been called the capital of the world. The institutions which comprise the teaching facilities of the Department are described below. Now part of Columbia University, the College of Physicians and Surgeons was founded in 1767 and was the first school in North America to award doctoral degrees in medicine. 'P&S' has developed extensive new facilities over the past few years, including the Hammer Health Sciences Center - a 20-story structure housing an excellent medical library, amphitheatre and teaching facilities. The medical school is considered to be among the finest in America, and has traditionally been one of the nation's primary sources of academicians, investigators and clinical teachers. The core New York Presbyterian Hospital structure, adjacent to the NYSPI, is the 745-bed Milstein Hospital building, which has expanded the hospital's advanced medical procedures and its critical care capability.

We've found
49 trials
at this facility
Cocaine Dependence Clinical Trial
Imaging the Neurobiology of a Behavioral Treatment for Cocaine Dependence
Status: Enrolling
Updated: 9/14/2006
mi
from
New York, NY
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Major Depressive Disorder Clinical Trial
Cognitive Behavior Therapy for Depression Depression
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Immunology / Infectious Diseases, Other Clinical Trial
Return to Work Randomized Controlled Trial: Counseling After Fatigue Treatment in HIV/AIDS
Status: Enrolling
Updated: 2/13/2018
mi
from
New York, NY
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Alcohol or Other Drugs Use Clinical Trial
HealthCall-S: A Pilot Study Targeting Concurrent Non-injection Drug Use and Alcohol in HIV Primary Care Clinics
Status: Enrolling
Updated: 7/13/2015
mi
from
New York, NY
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
A Study of L-DOPA for Depression and Slowing in Older Adults
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Treatment Resistant Depression Clinical Trial
Neuroimaging in Patients Undergoing TMS for Depression
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Clinical High Risk for Psychosis Clinical Trial
Glutamate Reducing Interventions in Schizophrenia
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
New York, NY
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Opioid-use Disorder Clinical Trial
Buprenorphine as Adjunct to Outpatient Induction Onto Vivitrol
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
New York, NY
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Opioid-use Disorder Clinical Trial
A Strategy to Improve Success of Treatment Discontinuation in Buprenorphine Responders
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
New York, NY
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Opioid Dependence Clinical Trial
Facilitating Rapid Naltrexone Initiation
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
New York, NY
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Social Anxiety Disorder Clinical Trial
Computer-Based Treatment for Social Anxiety Disorder
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Obsessive Compulsive Disorder (OCD) Clinical Trial
Feasibility, Acceptability, and Preliminary Efficacy of a Mobile App (nOCD) for OCD
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Schizophrenia Clinical Trial
A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic Medication
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
New York, NY
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Posttraumatic Stress Disorder (PTSD) Clinical Trial
Attention-Bias Modification Treatment for PTSD
Status: Enrolling
Updated: 4/14/2016
mi
from
New York, NY
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Endocrinology, Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older Adults
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
New York, NY
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Attention Deficit Hyperactivity Disorder Clinical Trial
An fMRI Study of Stimulant vs. Non-Stimulant Treatment of ADHD
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Clinical High Risk for Psychosis Clinical Trial
Gabapentin in Patients at Clinical Risk for Psychosis
Status: Enrolling, Phase I, II
Updated: 12/22/2016
mi
from
New York, NY
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Psychiatry / Psychology, Other Clinical Trial
Treating Hearing Loss to Improve Mood and Cognition in Older Adults
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
New York, NY
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Psychiatry / Psychology Clinical Trial
Pharmacogenetics of Naltrexone for Stimulant Abuse
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
New York, NY
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Psychiatry / Psychology Clinical Trial
NRX101 Glx Biomarker Validation Study
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
New York, NY
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Psychiatry / Psychology Clinical Trial
Evaluation of the Communities of Healing Mentorship/Support Group Program: Assessment of Preliminary Efficacy
Status: Enrolling
Updated: 2/6/2018
mi
from
New York, NY
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Major Depressive Disorder Clinical Trial
Contact: Developing New Clinical Management Strategies
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
New York, NY
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PTSD Clinical Trial
Reflective Function as a Mediator of Interpersonal Psychotherapy (IPT)
Status: Enrolling, Phase
Updated: 12/31/1969
mi
from
New York, NY
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Social Anxiety Disorder Clinical Trial
A Novel Computer-Based Therapy for Social Anxiety
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Immunology / Infectious Diseases, Neurology Clinical Trial
Anti-viral Therapy in Alzheimer's Disease
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
New York, NY
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Schizophrenia Clinical Trial
This Study Tests Whether BI 409306 Prevents Patients With Schizophrenia From Becoming Worse. This Study Looks at How Well Patients Tolerate BI 409306 and How Effective it is Over 6 Months
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
New York, NY
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Stigma Clinical Trial
Training Church Leaders in Mental Health First Aid
Status: Enrolling, Phase
Updated: 12/31/1969
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from
New York, NY
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Alcohol Use Disorder Clinical Trial
The Effect of rTMS to the Prefrontal Cortex in Alcohol Use Disorder
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Major Depressive Disorder Clinical Trial
Mechanisms of Antidepressant Non-Response in Late-Life Depression
Status: Enrolling
Updated: 12/31/1969
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from
New York, NY
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Obsessive-Compulsive Disorder Clinical Trial
BHV-4157 in Adult Subjects With Obsessive Compulsive Disorder
Status: Enrolling, Phase II, III
Updated: 12/31/1969
mi
from
New York, NY
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Psychotic Disorders Clinical Trial
This Study Tests Whether BI 409306 Prevents Patients With a Specific Type of Mental Illness (Attenuated Psychosis Syndrome) From Becoming Worse. This Study Looks at How Well Patients Tolerate the Medicine and How Effective it is Over 1 Year
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
New York, NY
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Suicide, Attempted Clinical Trial
Safety Planning Intervention to Reduce Short Term Risk
Status: Enrolling
Updated: 12/31/1969
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New York, NY
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Glioblastoma Clinical Trial
Tolerability of Cannabis in Patients Receiving Concurrent Chemoradiation for Glioblastoma
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
New York, NY
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Obsessive-Compulsive Disorder Clinical Trial
Effects of Marijuana on Symptoms of OCD
Status: Enrolling, Phase I, II
Updated: 12/31/1969
mi
from
New York, NY
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Schizophrenia Clinical Trial
CVN058 Effect on Mismatch Negativity in Schizophrenics
Status: Enrolling, Phase I
Updated: 12/31/1969
mi
from
New York, NY
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Heroin Dependence Clinical Trial
Buprenorphine Stabilization and Induction Onto Vivitrol for Heroin-dependent Individuals
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
New York, NY
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Schizophrenia Clinical Trial
ITI-007 (Lumateperone Tosylate) for Schizophrenia
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
New York, NY
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Anorexia Nervosa Clinical Trial
Inpatient Exposure Therapy and Response Prevention & Cognitive Remediation Therapy for Anorexia Nervosa
Status: Enrolling
Updated: 8/2/2010
mi
from
New York, NY
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
Wake Therapy in the Treatment of Depression
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Neurology, Psychiatry / Psychology Clinical Trial
Treatment of Psychosis and Agitation in Alzheimer's Disease
Status: Enrolling, Phase II
Updated: 12/31/1969
mi
from
New York, NY
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Psychiatry / Psychology Clinical Trial
Remediation of Auditory Recognition in Schizophrenia With tDCS
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Neurology, Psychiatry / Psychology Clinical Trial
Cognitive Training and Neuroplasticity in Mild Cognitive Impairment
Status: Enrolling
Updated: 12/31/1969
mi
from
New York, NY
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Psychiatry / Psychology Clinical Trial
Combined Treatment of Prolonged Exposure and Pramipexole for Posttraumatic Stress Disorder and Depression
Status: Enrolling, Phase III
Updated: 12/31/1969
mi
from
New York, NY
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Psychiatry / Psychology, Pulmonary / Respiratory Diseases Clinical Trial
L-DOPA vs. Placebo for Depression and Psychomotor Slowing in Older Adults
Status: Enrolling, Phase IV
Updated: 12/31/1969
mi
from
New York, NY
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Chronic Pain Clinical Trial
Imaging the Effects of rTMS on Chronic Pain
Status: Upcoming, Phase I
Updated: 2/19/2016
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from
New York, NY
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Psychiatry / Psychology Clinical Trial
OnTrack>An Online Role-Playing Game for Young People With First Episode Psychosis
Status: Upcoming
Updated: 12/31/1969
mi
from
New York, NY
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Cigarette Smoking Clinical Trial
Effects of Nicotine Replacement Therapy and D-cycloserine on Nicotine Treatment Seekers
Status: Upcoming, Phase II
Updated: 7/22/2013
mi
from
New York, NY
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Psychiatry / Psychology Clinical Trial
D-serine Augmentation of Neuroplasticity
Status: Upcoming, Phase I, II
Updated: 12/31/1969
mi
from
New York, NY
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Post Treatment Lyme Disease Syndrome Clinical Trial
Meditation and Stretching for Post Treatment Lyme Disease Syndrome
Status: Upcoming
Updated: 1/26/2015
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from
New York, NY
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