Evaluation of ETC-1002 in Patients With Hypercholesterolemia and Hypertension



Status:Completed
Conditions:High Blood Pressure (Hypertension), High Cholesterol
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 80
Updated:3/31/2019
Start Date:June 2014
End Date:July 2015

Use our guide to learn which trials are right for you!

A Placebo-Controlled, Randomized, Double-Blind, Parallel Group Study to Evaluate the Efficacy and Safety of ETC-1002 in Patients With Hypercholesterolemia and Hypertension

This Phase 2 study will assess the efficacy and safety of ETC-1002 monotherapy versus placebo
in patients with hypercholesterolemia and hypertension.


Inclusion Criteria:

- Mean 24-hour ambulatory SBP greater than or equal to 130 mmHg

- or- Mean 24-hour ambulatory DBP greater than or equal to 80 mmHg

- Fasting LDL-C between 100 and 220 mg/dL

- Fasting triglycerides less than 400 mg/dL

- Body mass index (BMI) between 18 and 45 kg/m2

Exclusion Criteria:

- Known or suspected secondary hypertension or history of malignant hypertension

- Taking more than two anti-hypertension medications at the first visit

- History or current clinically significant cardiovascular disease

- History or current type 1 diabetes or type 2 diabetes
We found this trial at
35
sites
?
mi
from
Kansas City, KS
Click here to add this to my saved trials
?
mi
from
Auburn, ME
Click here to add this to my saved trials
?
mi
from
Berlin, NJ
Click here to add this to my saved trials
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
?
mi
from
Butte, MT
Click here to add this to my saved trials
?
mi
from
Chandler, AZ
Click here to add this to my saved trials
Charleston, South Carolina 29412
?
mi
from
Charleston, SC
Click here to add this to my saved trials
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
?
mi
from
Corpus Christi, TX
Click here to add this to my saved trials
?
mi
from
Dallas, TX
Click here to add this to my saved trials
?
mi
from
Dallas, TX
Click here to add this to my saved trials
?
mi
from
DeLand, FL
Click here to add this to my saved trials
Downingtown, Pennsylvania 19335
?
mi
from
Downingtown, PA
Click here to add this to my saved trials
?
mi
from
Endwell, NY
Click here to add this to my saved trials
?
mi
from
Eugene, OR
Click here to add this to my saved trials
?
mi
from
Fort Lauderdale, FL
Click here to add this to my saved trials
?
mi
from
Gurnee, IL
Click here to add this to my saved trials
?
mi
from
Hialeah, FL
Click here to add this to my saved trials
?
mi
from
Houston, TX
Click here to add this to my saved trials
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
?
mi
from
Kenosha, WI
Click here to add this to my saved trials
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
?
mi
from
Madison, WI
Click here to add this to my saved trials
Olive Branch, Mississippi 38654
?
mi
from
Olive Branch, MS
Click here to add this to my saved trials
?
mi
from
Paducah, KY
Click here to add this to my saved trials
?
mi
from
Pembroke Pines, FL
Click here to add this to my saved trials
?
mi
from
Pembroke Pines, FL
Click here to add this to my saved trials
?
mi
from
Phoenix, AZ
Click here to add this to my saved trials
?
mi
from
Port Orange, FL
Click here to add this to my saved trials
?
mi
from
Salt Lake City, UT
Click here to add this to my saved trials
?
mi
from
Salt Lake City, UT
Click here to add this to my saved trials
?
mi
from
Simpsonville, SC
Click here to add this to my saved trials
?
mi
from
Willoughby Hills, OH
Click here to add this to my saved trials
Wilmington, North Carolina 28401
?
mi
from
Wilmington, NC
Click here to add this to my saved trials